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KMID : 0356420080260020091
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Journal of Korean Andrology
2008 Volume.26 No. 2 p.91 ~ p.95
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Correlation between Serum Testosterone and Lower Urinary Tract Symptoms in Men with Hypogonadism Symptoms
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Sohn Dong-Wan
Choe Hyun-Sop
Lee Nam-Seok
Kim Sung-Dae
Kim Doo-Bae
Kim Hyun-Woo
Kim Sae-Woong
Lee Byung-Hee
Cho Yong-Hyun
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Abstract
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Purpose: We performed this study to estimate the correlation of serum testosterone and lower urinary tract
symptom (LUTS) in adult hypogonadism patients.
Materials and Methods: Medical records of ninety men over forty years old who have LUTS, International Prostate Symptom Score (IPSS) above 7 were reviewed. The correlations of serum testosterone level withage, International Prostate Symptom Score (IPSS), prostate volume, prostate specific antigen (PSA) and maximal flow rate were assessed using Spearman test. The statistical differences of IPSS, prostate volume, PSA and maximal flow rate in 3 groups of patients divided by serum testosterone levels(<2.0, 2.0-3.5, >3.5 ng/ml).
Results: Serum testosterone level decreased according to increase of age (r=-0.28, p=0.07). Serum testosterone has no significant correlation with IPSS, prostate volume, PSA and maximal flow rate. There was no significant difference of IPSS, prostate volume, PSA and maximal flow rate according to the levels of testosterone.
Conclusions: Emerging from this analysis, clinical indexes of LUTS may not be connected with testosteronelevel
and LUTS may not be affected by hypogonadism. Further more objective and sophisticated studies with large
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KEYWORD
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Lowerurinarytractsymptom, Testosterone, Hypogonadism
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